Available for collaboration · Open science

Dr. Louise
Cerdeira ✦

Computational biologist and software engineer building open platforms that turn pathogen genomes into public-health decisions. Creator of AMRnet, TyphiNET, PlasmidNET, and InfectoNET.

5,300+Citations
34h-index
143Publications
4Live platforms
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Scientist by training,
engineer by practice.

Portrait of Dr. Louise Cerdeira

I'm a Brazilian computational biologist living and working in the UK. My day-to-day sits at the intersection of microbial genomics, web platforms, and global public health — building the tools that make genomic surveillance accessible to anyone, anywhere.

I trained as a computer scientist before moving into bioinformatics — a PhD at the University of São Paulo on the comparative genomics of multidrug-resistant Klebsiella pneumoniae, then postdoctoral and engineering roles across three continents. Today I lead the design and development of AMRnet, TyphiNET, PlasmidNET, and InfectoNET — open surveillance dashboards used by ministries, reference labs, and researchers across the globe.

I care a lot about open science, the One Health framing of antimicrobial resistance, and making high-performance bioinformatics affordable for low- and middle-income countries — which is increasingly where my newer work on GPU-accelerated aligners and embedded pipelines lives.

  • RoleComputational Biologist · Software Engineer · Platform Lead
  • Based inUnited Kingdom · 🇧🇷 originally Brazil
  • ORCID0000-0002-4495-2615
  • Scholar5,300+ citations · h-index 34
  • LanguagesEnglish · Portuguese · Spanish
  • CurrentlyAMR copy-number variation in Klebsiella; GPU-native aligners for LMIC surveillance

What I work on.

My research uses microbial whole-genome sequencing and software engineering to track, understand, and contain antimicrobial-resistant pathogens — connecting bench, bioinformatics, and public-health practice.

Genomic surveillance of AMR

Dashboards and pipelines for tracking resistance in WHO-priority pathogens — Klebsiella, Salmonella, E. coli, M. tuberculosis.

One Health

Resistance crosses people, animals, food, and the environment. I work on shared genomic infrastructure that lets us see all of it at once.

Vector biology

Insecticide resistance in Anopheles and Wolbachia endosymbionts — with the Heinz Lab and MalariaGEN.

GPU bioinformatics for LMICs

Building cloud-native and embedded-system aligners (Dragon, CNVRock) so sequencing analysis doesn't need a HPC cluster.

Book · Monograph · Portuguese

Montagem ab initio de genoma bacteriano

utilizando sequências curtas pareadas

A monograph (based on my MSc work) demonstrating that bacterial genomes can be assembled ab initio from short 25-nucleotide paired-end reads — one of the foundational bioinformatics challenges of the early NGS era, and where my long love affair with microbial genomics began.

Bioinformatics NGS Bacterial genomics ISBN 978-3-639-68490-2

Selected publications

  1. 2026
    AMRnet: a data visualization platform to interactively explore pathogen variants and antimicrobial resistance Cerdeira LT, Dyson ZA, Sharma V, Maranga M, Foster-Nyarko E, Carey ME, Holt KE — Nucleic Acids Research, 54(D1):D691–D702
  2. 2025
    The TyphiNET data visualisation dashboard: unlocking Salmonella Typhi genomics data to support public health Dyson ZA, Cerdeira L, Sharma V, Carey ME, Holt KE & Global Typhoid Genomics Consortium — Genome Medicine
  3. 2023
    Genome-wide association studies reveal novel loci associated with pyrethroid and organophosphate resistance in Anopheles gambiae and An. coluzzii Lucas ER, Nagi SC, Egyir-Yawson A, et al., Cerdeira L, et al. — Nature Communications, 14:4946
  4. 2022
    WHO Critical Priority Escherichia coli as One Health challenge for a post-pandemic scenario Fuga B, Sellera FP, Cerdeira L, et al. — Microbiology Spectrum, 10(2)
  5. 2022
    Linear plasmids in Klebsiella and other Enterobacteriaceae Hawkey J, Cottingham H, Tokolyi A, Wick RR, Judd LM, Cerdeira L, et al. — Microbial Genomics
  6. 2021
    A genomic surveillance framework and genotyping tool for Klebsiella pneumoniae and its related species complex Lam MMC, Wick RR, Watts SC, Cerdeira LT, Wyres KL, Holt KE — Nature Communications, 12:4188 · 1,000+ citations
  7. 2021
    Trycycler: consensus long-read assemblies for bacterial genomes Wick RR, Judd LM, Cerdeira LT, Hawkey J, Méric G, Vezina B, Wyres KL, Holt KE — Genome Biology, 22:266
  8. 2019
    Small IncQ1 and Col-like plasmids harbouring blaKPC-2 in high-risk lineages of Klebsiella pneumoniae CG258 Cerdeira LT, Lam MMC, Wyres KL, Wick RR, Judd LM, Lopes R, et al. — Microbial Drug Resistance
  9. 2013
    The genome of Anopheles darlingi, the main neotropical malaria vector Marinotti O, Cerqueira GC, de Almeida LGP, et al., Cerdeira LT, et al. — Nucleic Acids Research, 41(15):7387–7400

Full list on Google Scholar → ORCID record

A worldwide
network of co-authors.

Published research with colleagues across six continents — surveillance teams, reference labs, universities, ministries of health, and open-source communities. Hover any marker to see the country.

32+Countries
6Continents
200+Co-authors
  • 🇧🇷 Brazil
  • 🇬🇧 UK
  • 🇦🇺 Australia
  • 🇺🇸 USA
  • 🇮🇳 India
  • 🇿🇦 South Africa
  • 🇰🇪 Kenya
  • 🇬🇭 Ghana
  • 🇫🇷 France
  • 🇩🇪 Germany
  • 🇮🇩 Indonesia
  • 🇸🇬 Singapore

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Things I've built.

Open platforms, pipelines, and tools — most of them used in production by public-health teams or in active research.

Live · Co-author

Kleborate

Open command-line tool for typing Klebsiella pneumoniae genomes — MLST, virulence, AMR. The companion Nature Communications paper has been cited over 1,000 times.

PythonGenotypingCLI

Live · Co-author

Trycycler

Consensus long-read assembler for bacterial genomes. Produces near-perfect chromosomes from Nanopore and PacBio data. Widely adopted across the long-read assembly community.

PythonLong-readsAssembly

In development

Dragon

A cloud-native, signal-aware aligner for surveillance-scale microbial genomics — BWT, FM-index, coloured de Bruijn graphs, ML signal correction. Written in Rust, designed to fit on commodity / edge hardware.

WIP RustGPU

In development

CNVRock

Variational-autoencoder approach to AMR-gene copy-number variation across the K. pneumoniae species complex. Where the resistance is, and how much of it.

WIP PythonPyTorch

Live

InfectoNET

Genomic-epidemiology dashboard tracking emerging and re-emerging pathogens worldwide — one platform, many threats. Built to make outbreak data legible to clinicians, public-health teams, and the public.

Creator TypeScriptNext.js

Live

PlasmidNET

Interactive dashboard for exploring plasmid sequences across species — typing, AMR cargo, mobility. Built on years of work on mobile genetic elements and the way resistance actually travels between bugs.

Creator PythonDash

Live

BraSeqTB

A Nextflow pipeline for AMR detection in Mycobacterium tuberculosis, designed for the Brazilian National TB Reference Network.

NextflowTB

Live · Collaboration

MINUUR

Reproducible Snakemake pipeline that recovers metagenomic data from Aedes aegypti whole-genome sequencing reads. With the Heinz Lab at LSTM.

SnakemakeMetagenomics

Career, briefly.

  1. 2023 — Present

    Lead Software Engineer · Computational Biologist

    System architecture and lead development of AMRnet; co-coordinator of TyphiNET; design and launch of PlasmidNET and InfectoNET. Open science, internationalisation, multi-pathogen surveillance.

  2. 2022 — 2023

    Postdoctoral Bioinformatician · Vector Biology

    Wolbachia endosymbionts, Aedes microbiome (MINUUR), MalariaGEN / PAMCA Anopheles genomic-surveillance training.

  3. 2020 — 2022

    Research Software Engineer · Infectious Diseases

    Built the initial TyphiNET dashboard; contributed to Kleborate and Trycycler. Australia.

  4. 2015 — 2019

    University of São Paulo · PhD in Sciences (with honourable mention)

    Comparative genomics of multidrug-resistant K. pneumoniae CG258 — IncQ1 plasmids, KPC-2 mobility. FAPESP-funded.

  5. 2011 — 2015

    Professor & Senior Systems Analyst · Brazil

    Earlier life as an academic computer scientist and IT engineer in Brazil — bridges that still inform how I build research software today.

  6. 2009 — 2011

    Federal University of Pará · MSc in Bioinformatics

    Where computer science met biology, and never let go.

Latest from GitHub.

A live feed of my most recently updated public repositories — bioinformatics, web tooling, and occasional side quests.

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Notes from the lab and the editor.

Short essays on the things I actually think about — open science, software engineering for research, and the weird shape of the field where they meet.

All posts →

Photography, poems, and a podcast.

Outside the terminal I keep a camera, a notebook, and a microphone within reach. Some of what that produces ends up here.

Watch / Listen

  • YouTube · LuLu Channel

    Science, in plain Portuguese (and a little English)

    Short videos on what I'm working on, what I just read, and how to actually run a pipeline. [TODO — add channel URL]

  • Podcast · A Popcorn Called Wilson

    Long-form conversations on science and the rest

    A side project with friends — bioinformatics, books, film, life in academia. [TODO — add podcast URL]

A featured talk

[TODO]

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Conference talks · workshops · interviews

Let's build something useful.

Open to collaborations on genomic surveillance, AMR, public-health platforms, and bioinformatics software. Always happy to talk to students considering computational biology.